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Separation of Large ssDNA Oligomers on HALO® OLIGO C18

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Advantages of HALO® OLIGO C18

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HALO® OLIGO C18 Lot-to-Lot Reproducibility

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Oligonucleotide Performance Mix on OLIGO C18

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Separation of Oligonucleotide Ladder via LC-MS

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Oligonucleotide Ladder via UV Detection

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Increased Peak Capacity of Trastuzumab Tryptic Digest

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Reduced Trastuzumab

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Amino Acids by HILIC – Single Quadrupole Mass Detection

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PCS C18 Loading Studies

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PCS C18 vs C18 Peptide Panel

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Rapid Peptide Separation

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Insulin Variants

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Trastuzumab Digest Sensitivity Improvement

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Trastuzumab Peptides

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Oligonucleotide Ladder Separation

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Impact of Column ID on Sensitivity for Peptides and Proteins

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LC-MS Analysis of an ADC Mimic

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Demonstration of Increased Sensitivity With Reduced Trastuzumab Using a 1.5 mm ID Stainless Steel Column

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Increased Sensitivity of Intact Trastuzumab Using a 1.5 mm ID Stainless Steel Column

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Increased Sensitivity and Solvent Savings of Trastuzumab Tryptic Digest Using a 1.5 mm ID Stainless Steel Column

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Sensitivity Increase of Mixed Proteins Through the Use of a 1.5 mm ID Stainless Steel Column

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IdeS Digested mAb

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Deamidation Products of the NIST mAb

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HALO Glycan Lot to Lot Reproducibility

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Peptide Analysis of Bee Venom Assay for Antimicrobial Properties

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Peptide and Protein Mix

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IgG2-B Monoclonal Antibody

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Effect of Silica Pore Size on Protein Separations

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Comparison Separation of Seven Peptides

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Peptides and Small Proteins on HALO® Peptide ES-C18

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2 µm Peptide ES-C18 Lot Reproducibility

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Very High Peak Capacity With a 2 µm Peptide Column

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Fast Peptide Separation

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Comparison Separation of Four Small Proteins

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Analysis of Apotransferrin Tryptic Digest

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Procainamide-Labeled Dextran Standards

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PNGase-Released and Labeled N-Glycans by HILIC

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Apotransferrin Tryptic Digest

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Protein Separation on a 1000 A Column

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Reduced IgG1 (Trastuzumab) Retention Comparison

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Effect of Acid Modifiers on Intact mAb Peak Shape

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Improved Protein Separations with HALO® Protein C4 Compared to Totally Porous C4

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LC-MS Analysis of Reduced IgG1 Monoclonal Antibody Fragments

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Effect of Temperature on the Separation of Proteins

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Enhanced Selectivity for Tryptic Digest using LC-MS

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Effect of Pore Size on Protein Peak Shape and Width

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Enhanced Selectivity for the Separation of Peptides Comparing Three Different 160 A Bonded Phases

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Rapid Peptide Mapping of an Adalimumab (Humira) Digest

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High Temperature, Low pH Stability With a 2 µm Peptide Column

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High Temperature – Low pH Stability of HALO® 1000 A ES-C18

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IgG2 Selectivity Comparison on 1000 A C4, ES-C18, and Diphenyl Phases

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LC-MS Analysis of Trastuzumab Using a 1000 A C4 Column

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1000 A C4 Protein Column for a High Resolution Separation of a Monoclonal Antibody

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Increased Resolution of a 400 Å Diphenyl Compared to a 300 Å Diphenyl