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Technical Support

Making Good Connections with the Improved Avantor Ultrasphere Column Hardware

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Technical Support

Avantor® ACE® Excel-Bioanalytical Oligo Buffer Recommendations

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Technical Reports

UHPLC & HPLC Method Development for Pharmaceutical-Related Substance

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Technical Notes

Chromatography Solutions for the Analysis of Nitrosamines

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Technical Notes

Reducing Particle Size, Column ID, and Length to Increase Throughput Using SPP Columns with Sidenafil Case Study

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Catalogs

Avantor® ACE® Excel 1.7 um Catalog

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New HILIC Bonded-Phase Fused-Core Columns Demonstrating Highly Efficient Separations

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Technical Notes

MAC-MOD® SafetyCaps Material Data Sheet

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Technical Notes

Reversed-Phase Method Development Flow Chart

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HILIC Method Development Flow Chart

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Technical Notes

HPLC and UHPLC System Shutdown and Reactivation Advice

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Column Regeneration for Partisil and Partisphere Ion-Exchange Columns

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Column Cleaning, Regeneration and Storage of Silica-Based Columns

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Technical Reports

PFAS Analysis

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Technical Reports

Rapid and High Resolution Solutions for PFAS Analysis

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USP Column Codes

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Transferring LC Methods Between Different Instruments

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The Effect of Sample Diluent on Peak Shape

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Analyte Properties – pKa, logP and logD

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Increasing HPLC and UHPLC Sample Throughput – Doing More in Less Time

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Technical Reports

FDA LC-MS-MS Method for the Determination of NDMA in Ranitidine

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LC-UV Detection of Cannabinoids and Terpenes for Potency Testing of Medicinal Cannabis

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High Resolution Separation of BSA Tryptic Digest

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Catalogs

UltraSphere® Catalog

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LabNotes

New Phases With Additional Selectivity for Method Development and the Analysis of Small Molecules

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White Papers

Environmental Analyses of Harmful Chemical and Organic Compounds Using Superficially Porous Particle Separations

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White Papers

Achieving Successful Method Translations in Liquid Chromatography

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White Papers

A Novel Approach to Glycan Method Development for Biotherapeutics using Superficially Porous Particle Technology

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Webinars

Best Practices for Limiting Hazardous Solvent Exposure with SafetyCaps and Waste Containment for HPLC and UHPLC Systems

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RPLC Method Development Strategies Using Stationary Phase and Mobile Phase Screening, and Some Helpful Tools and Tips

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Catalogs

Avantor® ACE® Catalog

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Presentations

LC and LC-MS of Intact Protein Biotherapeutics and their Variants and Panel Discussion With Industry Experts

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The Importance of Superficially Porous Particles in Modernizing HPLC Methods

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LabNotes

Accelerated Method Development with Novel Stationary Phase Chemistries

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LabNotes

LC Method Development Using a Unified Column Screening and Retention Modeling Approach

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LabNotes

Factors That Can Affect the Stability, Performance, and Lifetime of Silica-based RPLC Columns

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LabNotes

Sunscreen Applications

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The Effect of Neonicotinoids on Bees and the Environment

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Method Development Using Solid-Core Particle Columns

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LabNotes

An Overview of Systematic RPLC Method Development Using Multiple Organic Modifiers and Different pH Buffers

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Webinars

Using Selectivity to Optimize Resolution for Improved LC and LC-MS Method Development

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Webinars

UHPLC and HPLC Method Development for Pharmaceutical-Related Substances

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Theory and Practice of Developing LC Methods with Solid-Core Particle Columns

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LC and LC-MS of Intact Protein Biotherapeutics and their Variants and Panel Discussion

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HILIC Practical Tips and Guidance for Method Development

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Exploiting pH as a Part of Your RPLC Method Development Strategy

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Webinars

A Streamlined Approach for Reversed-Phase Method Development Using Combined Column Screening and Software Modeling

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Posters

Comparing HILIC and RP for LC-MS Analysis of O-HexNAc Modified Peptides

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Exploring HPLC and UHPLC Chromatographic Selectivity With Low and High pH Eluents

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High Efficiency LC-MS Analysis of O-HexNAc Modified Peptides

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Posters

High Efficiency LC-MS Analysis of O-GlcNAc Modified Synthetic Peptides

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Presentations

Larger Superficially Porous Particles – The Long and Short of it for HPLC Separations

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Optimization of Reversed-Phase HPLC Separations of Biomolecules using HALO® Protein and HALO®-5 Peptide

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Presentations

Particle Size Considerations of Superficially Porous Particles

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Exploring Low And High pH Eluents Using A New Silica-Based Extended pH Range C18 Column For Analysis Of Amphetamines and Opiates From Urine By LC-MS-MS

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Exploring The Power Of Chromatographic Selectivity For Polar & Non-Polar Analytes With A Unique HPLC-UHPLC Polar Embedded Stationary Phase

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Presentations

Speed and Resolution with 5-Micron Superficially Porous Particles

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Optimized Superficially Porous Particles for Peptide and Protein Analysis

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Intact Protein and Glycoprotein Separations by HILIC

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Bioseparations with 3.4- and 5-Micron Wide-Pore Superficially Porous Particles

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Presentations

Superficially Porous Particles for Peptide and Protein Analysis

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Posters

Application of Fused-Core Penta-HILIC for High Performance Separations of Nucleobases, Nucleosides and Nucleotides

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Presentations

Novel wide-pore SPPs for Biomacromolecular Separations

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Presentations

Superficially Porous Silica Particle Technology Developments for Pharma and Biopharma Applications

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Presentations

Chromatographic Effects Of Varying Particle Size And Size Distributions Of Superficially Porous Particles

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Presentations

Novel Hydrophilic Bonded-Phase Fused-Core Particles for Highly Efficient HILIC Separations

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White Papers

Improving Liquid Chromatographic Separations in Clinical Analysis by Utilizing Recent Developments in Column Technology

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Considerations and Best Practices for Mobile Phase Buffer Selection and pH Control for LC and LC-MS Method Development

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Catalogs

Avantor® ACE® UltraCore Catalog

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Application Guides

HALO® Application Guide

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Avantor® ACE® Complete Application Guide

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Working With UHPLC – Accelerating Method Development, Speeding Up Routine Analyses, and Achieving Ultra High Resolution

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Understanding and Overcoming Separation Challenges in the Biological Drug Development Process

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Take Your UHPLC and HPLC Methods to the Next Level of Speed and Resolution

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Application Packets

Avantor® ACE® UHPLC Application Packet

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Avantor® ACE® LCMS Application Packet

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Technical Reports

Troubleshooting Guide by John Dolan

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Modifying Agilent 1100 HPLC Systems to Achieve “UHPLC-like” Performance With HALO® Fused-Core® Particles

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How to Measure and Reduce HPLC Equipment Extra Column Volume

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Technical Notes

Separation of Paracetamol and Related Substances following European Pharmacopoeia Method 9.4

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High Resolution LC-MS Separations of Edible Oils

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A Conversation on Retention and Resolution

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Buffer Selection Guide by John Dolan

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Guide to Labelling Mobile Phase Buffers

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Using Narrow Bore Columns to Enhance Sensitivity for LC-UV and LC-MS Analyses

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Gradient Method Translation using the Avantor® ACE® Translation Tool

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Creating the Correct Environment for Analyzing Reducing Sugars

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Solid-Core Technology

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How to Determine Extra Column Dispersion and Extra Column Volume

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How to Determine Column Volume and Particle Porosity

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Understanding the Relationship Between Particle Size, Performance and Pressure

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Technical Support

Avantor® ACE® SuperC18 Buffer Recommendations

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Practical Ultra High Performance Liquid Chromatography (UHPLC)

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Chromatographic Band Broadening and the van Deemter Equation

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The Role of Methanol and Acetonitrile as Organic Modifiers in Reversed-Phase Liquid Chromatography

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Gradient Chromatography

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UHPLC Fittings and Connections

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The Fundamental Resolution Equation and the Impact of k, N and α

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Basic Column Care and Cleaning

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How to Calculate Resolution