Superficially porous particles deliver striking improvements to chromatographic separations compared to fully porous particles. However, it is important to optimize the instrumentation in order to gain the most benefit from this technology for both isocratic and gradient methods. Following new USP guidelines for gradient method modernization enables both FPP and SPP methods to be improved for speed and solvent savings.
Author: Dr. Stephanie Schuster, Senior Technical Support Scientist, Advanced Materials Technology